opioid dependence

Helpful Links

There are many resources available to you and your support network to better understand and cope with opioid dependence. Some resources, like the American Board of Addiction Medicine and the American Board of Psychiatry and Neurology, can refer you to local addiction specialists and healthcare providers for treatment. Check out some of the recommended sites below.

These helpful links are provided as a public service and are for informational purposes only. No endorsement is made or implied.

American Board of Addiction Medicine

The American Board of Addiction Medicine is the nation’s first medical specialty board that certifies addiction medicine physicians across a range of specialties with the mission to increase access to and to improve the quality of addiction treatment.

abam.net

American Board of Psychiatry and Neurology

The American Board of Psychiatry and Neurology is a not-for-profit corporation that promotes excellence in practice through certification and maintenance of certification processes, and is a member of the American Board of Medical Specialties.

abpn.com
American Society of Addiction Medicine

The American Society of Addiction Medicine (ASAM), founded in 1954, is a professional medical society representing over 5000 physicians, clinicians, and associated professionals in the field of addiction medicine. ASAM is dedicated to increasing access and improving the quality of addiction treatment, educating physicians and the public, supporting research and prevention, and promoting the appropriate role of physicians in the care of patients with addiction.

asam.org
National Institute on Drug Abuse

The mission of the National Institute on Drug Abuse (NIDA) is to lead the nation in bringing the power of science to bear on drug abuse and addiction.

drugabuse.gov
Medicaid

Medicaid is a federal government program for families and individuals with low income and resources. Medicaid.gov provides state-by-state information on eligibility and enrollment.

medicaid.gov

Medicare

Medicare is a national social insurance program that guarantees access to health insurance for Americans aged 65 and older and people with disabilities. Medicare.gov offers information on Medicare coverage and plans as well as additional helpful resources.

medicare.gov
The National Alliance of Advocates for Buprenorphine Treatment

The National Alliance of Advocates for Buprenorphine Treatment (NAABT) is a nonprofit organization charged with the mission to educate the public about the disease of opioid dependence and treatment with buprenorphine.

naabt.org
Substance Abuse and Mental Health Services Administration

The Substance Abuse and Mental Health Services Administration was established by Congress in 1992 to reduce the impact of substance abuse and mental illness in American communities.

samhsa.gov

Ask your healthcare provider
about ZUBSOLV!

What is ZUBSOLV®?

ZUBSOLV® (buprenorphine and naloxone) sublingual tablet (CIII) is a prescription medicine used to treat adults who are addicted to opioid drugs (either prescription or illegal) as part of a complete treatment program that also includes counseling and behavioral therapy.

IMPORTANT SAFETY INFORMATION

  • Do not take ZUBSOLV if you are allergic to buprenorphine or naloxone as serious negative side effects, including anaphylactic shock, have been reported.

  • ZUBSOLV can cause serious and life-threatening breathing problems. Call your healthcare provider right away or get emergency help if (a) you feel faint, dizzy, or confused; (b) your breathing gets much slower than is normal for you; (c) you feel sleepy and uncoordinated; (d) you have blurred vision; (e) you have slurred speech; (f) you cannot think well or clearly; or (g) you have slowed reflexes and breathing. In an emergency, have family members tell the emergency department staff that you are physically dependent on an opioid and are being treated with ZUBSOLV.

  • ZUBSOLV contains buprenorphine, an opioid that can cause physical dependence with chronic use. Physical dependence is not the same as addiction. Your healthcare provider can tell you more about the difference between physical dependence and addiction. Do not stop taking ZUBSOLV without talking to your healthcare provider. You could become sick with uncomfortable withdrawal signs and symptoms because your body has become used to this medicine.

  • Your healthcare provider may monitor liver function before and during treatment with ZUBSOLV.

  • Keep ZUBSOLV in a secure place away from children. If a child accidentally takes ZUBSOLV, this is a medical emergency and can result in death. Get emergency help right away.

  • The most common side effects of ZUBSOLV include: headache, drug withdrawal syndrome, nausea, decrease in sleep (insomnia), vomiting, pain, increased sweating, swelling of the extremities, and constipation. Tell your healthcare provider about any side effect that bothers you or that does not go away.

  • Do not switch from ZUBSOLV to other medicines that contain buprenorphine without talking with your healthcare provider. The amount of buprenorphine in a dose of ZUBSOLV is not the same as the amount of buprenorphine in other medicines that contain buprenorphine. Your healthcare provider will prescribe a starting dose of buprenorphine that may be different than other buprenorphine-containing medicines you may have been taking.

  • ZUBSOLV is not for occasional or “as needed” use. An overdose, and even death, can happen if you take benzodiazepines, sedatives, tranquilizers, or alcohol while using ZUBSOLV. Ask your healthcare provider what you should do if you are taking one of these. You should not drink alcohol while taking ZUBSOLV, as this can lead to loss of consciousness or even death.

  • Do not inject (“shoot-up”) ZUBSOLV. Injecting ZUBSOLV may cause life-threatening infections and other serious health problems. Injecting ZUBSOLV may cause serious withdrawal symptoms such as pain, cramps, vomiting, diarrhea, anxiety, sleep problems, and cravings.

  • Before taking ZUBSOLV, tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

  • Before taking ZUBSOLV, tell your healthcare provider if you are pregnant or plan to become pregnant. If you take ZUBSOLV while pregnant, your baby may have signs of withdrawal at birth and that withdrawal is treatable. Talk to your healthcare provider if you are pregnant or plan to become pregnant.

  • Before taking ZUBSOLV, tell your healthcare provider if you are breastfeeding or plan to breastfeed. ZUBSOLV can pass into your breast milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby if you take ZUBSOLV. Monitor your baby for increased sleepiness and breathing problems.

  • Do not drive, operate heavy machinery, or perform any other dangerous activities until you know how ZUBSOLV affects you. Buprenorphine can cause drowsiness and slow reaction times. This may happen more often in the first few weeks of treatment when your dose is being changed, but can also happen if you drink alcohol or take other sedative drugs when you take ZUBSOLV.

  • ZUBSOLV is a controlled substance (CIII) because it contains buprenorphine, which can be a target for people who abuse prescription medicines or street drugs. Keep your ZUBSOLV in a safe place to protect it from theft. Never give your ZUBSOLV to anyone else; it can cause death or harm them. Selling or giving away this medicine is against the law.

This is not a complete list of negative side effects associated with ZUBSOLV. For a complete list please see full Prescribing Information.

To report negative side effects associated with taking ZUBSOLV, please call 1-888-982-7658. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information about ZUBSOLV (buprenorphine and naloxone) Sublingual Tablet (CIII), please see the respective full Prescribing Information and Medication Guide.